Coupling HA Molecules from Various Flu Strains Could Make Vaccines More Effective
Results from a recent study suggest coupling HA molecules from various flu strains could make flu vaccines more effective.
Study Shows IVIG Is Associated with Sepsis Mortality
A study published in Frontiers in Immunology has found the administration of intravenous immune globulin (IVIG) is associated with a reduction in sepsis mortality and favorable outcomes in laboratory parameters and the functional status, contributing to the ongoing debate on the efficacy of IVIG for sepsis.
Blood Test Can Predict How Long Vaccine Immunity Will Last
A study led by researchers at Stanford Medicine has shown that variation in vaccine durability can, in part, be attributed to a type of blood cell called megakaryocytes, typically implicated in blood clotting.
Lab Value Predictive of COVID-19 Disease Severity in Children
A study has found measurements of C-reactive protein (CRP), lactate dehydrogenase (LDH) and albumin are potentially predictive markers for disease severity in children hospitalized with COVID-19. The multi-center retrospective cohort study at four pediatric referral hospitals in Iran between April 2020 and March 2021 assessed the discriminative ability of laboratory and clinical parameters to pinpoint […]
FDA Approves Dupixent for Chronic Obstructive Pulmonary Disease
The U.S. Food and Drug Administration (FDA) has expanded its approval of Dupixent to chronic obstructive pulmonary disease (COPD). This permits Dupixent’s use as an add-on maintenance treatment of adults whose COPD is inadequately controlled by available therapies. The every-other-week injectable drug is now the first biologic therapy approved by FDA for treating COPD, and […]
Changes in Immune Cell Gene Activity May Indicate Probability of Developing MS
Individuals with multiple sclerosis (MS) have high levels of immune cells called cytotoxic T cells, which normally help kill cancer and cells infected by germs. In MS, these cells accumulate in areas with visible myelin damage, but until recent study results, the role the cells play in the disease had remained unknown. In a study […]
HIV Vaccine Elicits Potent Response in Nonhuman Primates
A study conducted by researchers at Weill Cornell Medicine has demonstrated that a series of six vaccinations containing a modified protein from the surface of HIV particles stimulated initial steps of a potent immune response in young nonhuman primates. According to the researchers, this difficult-to-achieve response represents an important step toward providing full and potentially […]
CSL Begins Enrollment for Hizentra Study for POTS
CSL Ltd. has begun enrolling U.S. patients in a Phase III late-stage randomized control trial to assess whether Hizentra subcutaneous immune globulin (SCIG) can alleviate symptoms of postural orthostatic tachycardia syndrome (POTS) — a blood circulation disorder that is one of the most common and disabling symptoms of long COVID with no approved therapies. The […]
mRNA Cancer Vaccine Begins Trials for Non-Small Cell Lung Cancer
An mRNA vaccine has entered human trials as a treatment for lung cancer. Unlike traditional cancer vaccines such as the HPV vaccine, BNT116 is a therapeutic cancer vaccine designed to reduce tumor growth in patients with cancer or prevent its recurrence. BNT116 contains the genetic code for six molecules frequently seen in non-small cell lung […]
Multi-Million Dollar Grant Awarded for Organ Transplantation Research
Researchers at the Terasaki Institute for Biomedical Innovation have been awarded a multi-million dollar grant from the National Institutes of Health (NIH) to advance research in organ transplantation and antibody mediated rejection. The research will focus on creating a state-of-the-art multi-organs-on-a-chip platform comprised of a vascularized liver-on-a-chip and heart-on-a-chip, with a fully integrated biosensor system […]
