Biosupply Trends Marketplace News
Monday, February 19, 2024

Latest COVID-19 Vaccines Provide Protection for Majority

eBST Newsletter Main Article
 

In this Issue

•  IVIG/Albumin Supply Index
•  Open Market Pricing
•  New Products from FFF
•  Current Medicare
IVIG / SCIG Rates
•  Resources
•  Subscribe to IG Living and BioSupply Trends Quarterly
 
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New Centers for Disease Control and Prevention data show the latest COVID-19 vaccines provide 54 percent protection against symptomatic infection among immunocompetent adults. The new formulations target the Omicron variant XBB.1.5, which was the predominant circulating strain for much of 2023. read more ]

 

FDA Approves Updated Warning Labels for Opioid Prescriptions

The U.S. Food and Drug Administration (FDA) has approved and implemented updated warning labels for all opioid prescriptions, part of a continuing effort to reduce unsafe opioid use and risk for overdose, as well as to urge healthcare professionals to take a more patient-centered approach when prescribing opioid analgesic products. read more ]

 

Fourth Dose of COVID-19 Vaccine Increases Protection in Rheumatic Disease Patients

A new study led by Mass General Brigham researchers suggests that the U.S. Centers for Disease Control and Prevention recommendation that patients receiving disease-modifying antirheumatic drugs receive a fourth dose of the mRNA vaccine in addition to the three-dose primary series to protect against COVID-19 saves lives and reduces hospitalizations among patients in this high-risk group. read more ]

 

Study Uses Flu Virus to Speed Up COVID-19 Antibodies

Researchers at the University of California, Riverside, have developed a vaccine to help speed up the process of making antibodies against SARS-CoV-2 by using preexisting immunity to the influenza virus. read more ]

Industry News

Industry News Image

From Takeda Pharmaceuticals

Takeda's GAMMAGARD LIQUID (immune globulin infusion [human] 10% solution) has been approved by the U.S. Food and Drug Administration as an intravenous immune globulin therapy to improve neuromuscular disability and impairment in adults with chronic inflammatory demyelinating polyneuropathy. It can be used as induction therapy, which includes an induction dose followed by maintenance doses. read more ]

From Valneva

The U.S. Food and Drug Administration has approved ALYGLO (immune globulin intravenous [IVIG], human-stwk) 10% liquid, formerly referred to as "GC5107," for the treatment of adult patients aged 17 years and older with primary humoral immunodeficiency. read more ]

From ADMA Biologics

ADMA Biologics' supplemental biologics license application to revise BIVIGAM's (immune globulin intravenous) prescribing information to expand the primary humoral immunodeficiency indication to pediatric patients 2 years of age and older has been approved by the U.S. Food and Drug Administration. read more ]

From Takeda Pharmaceuticals

The U.S. Food and Drug Administration has approved HYQVIA (immune globulin infusion 10% [human] with recombinant human hyaluronidase) for the treatment of chronic inflammatory demyelinating polyneuropathy as maintenance therapy to prevent the relapse of neuromuscular disability and impairment in adults. read more ]

IVIG & Albumin Supply Index

IVIG and Albumin Days On Hand
     
 
 
 
     

What's New at FFF

HEPARIN SODIUM (MEITHEAL PHARMACEUTICALS)

HEPARIN SODIUM injection is an anticoagulant indicated for prophylaxis and treatment of venous thrombosis and pulmonary embolism; prevention of postoperative deep venous thrombosis and pulmonary embolism in patients undergoing major abdominothoracic surgery or who, for other reasons, are at risk of developing thromboembolic disease; atrial fibrillation with embolization; treatment of acute and chronic consumptive coagulopathies (disseminated intravascular coagulation); prevention of clotting in arterial and cardiac surgery; prophylaxis and treatment of peripheral arterial embolism; and use as an anticoagulant in blood transfusion, extracorporeal circulation and dialysis procedures. It is supplied in single-dose vials in 1,000, 5,000 and 10,000 USP units per mL, and multi-dose vials in 10,000 USP units per 10 mL, 30,000 units per 30 mL, 50,000 units per 10 mL and 40,000 USP units per 4 mL, packaged in 25 vials per carton.

For more information about HEPARIN SODIUM, log in to biosupply.fffenterprises.com

HIBERIX (GLAXOSMITHKLINE)

HIBERIX is a vaccine indicated for active immunization for the prevention of invasive disease caused by Haemophilus influenza type b in children aged 6 weeks through 4 years (prior to fifth birthday). HIBERIX vial and vial presentation is supplied in a carton packaged without syringes or needles containing 10 single-dose vials of lyophilized antigen component and 10 single-dose vials of sterile saline diluent. HIBERIX vial and prefilled syringe presentation is supplied in a carton containing 10 single-dose vials of lyophilized antigen component and 10 single-dose prefilled ungraduated TIP-LOK syringes of sterile saline diluent packaged without needles.

For more information about HIBERIX, log in to biosupply.fffenterprises.com

WINRHO SDF (KAMADA INC.)

WINRHO SDF is a Rho(D) immune globulin intravenous (IGIV; human) indicated for immune thrombocytopenic purpura (ITP) to raise platelet counts in Rho(D) positive, non-splenectomized children with chronic or acute ITP, adults with chronic ITP and children and adults with ITP secondary to HIV infection; and as a suppression of Rhesus (Rh) isoimmunization in pregnancy and other obstetric conditions in non-sensitized Rho(D) negative women with an Rh-incompatible pregnancy, including routine antepartum and postpartum Rh prophylaxis and Rh prophylaxis in obstetric complications or invasive procedures, and incompatible transfusions in Rho(D)-negative individuals transfused with blood components containing Rho(D)-positive red blood cells. It is supplied in cartons containing a single-dose vial of 600 IU (120 mcg), 1,500 IU (300 mcg), 2,500 IU (500 mcg), 5,000 IU (1,000 mcg) or 15,000 IU (3,000 mcg) anti-Rho(D) IGIV and a package insert.

For more information about WINRHO SDF, log in to biosupply.fffenterprises.com

IVERMECTIN (MAYNE PHARMA)

IVERMECTIN cream is indicated for the treatment of inflammatory lesions of rosacea. It is supplied as a 45 gram 1% white to pale yellow cream in a laminated tube with a child-resistant cap.

For more information about IVERMECTIN, log in to biosupply.fffenterprises.com

ISOTRETINOIN CAPSULES (MAYNE PHARMA)

ISOTRETINOIN CAPSULES are indicated for the treatment of severe recalcitrant nodular acne. They are supplied in boxes of 30 with three prescription packs of 10 mg, 20 mg, 30 mg or 40 mg capsules.

For more information about ISOTRETINOIN CAPSULES, log in to biosupply.fffenterprises.com

BIJUVA (MAYNE PHARMA)

BIJUVA is a combination of an estrogen and progesterone indicated in a woman with a uterus for the treatment of moderate to severe vasomotor symptoms due to menopause. It is supplied as 0.5 mg/100 mg capsules and 1 mg/100 mg capsules in blister packages of 30.

For more information about BIJUVA, log in to biosupply.fffenterprises.com

MELPHALAN HYDROCHLORIDE (APOTEX CORP)

MELPHALAN HYDROCHLORIDE for injection is indicated for the palliative treatment of patients with multiple myeloma for whom oral therapy is not appropriate. It is supplied in a carton containing one single-dose clear glass vial of freeze-dried melphalan hydrochloride equivalent to 50 mg melphalan and one 10 mL clear glass vial of sterile diluent.

For more information about MELPHALAN HYDROCHLORIDE, log in to biosupply.fffenterprises.com

CUPRIC CHLORIDE (EXCELA PHARMA SCIENCES)

CUPRIC CHLORIDE injection, USP 0.4 mg/mL, is indicated for use as a supplement to intravenous solutions given for total parenteral nutrition to help maintain copper serum levels and to prevent depletion of endogenous stores and subsequent deficiency symptoms. It is supplied in 10 mL plastic vials in cartons of 10 and 25.

For more information about CUPRIC CHLORIDE, log in to biosupply.fffenterprises.com

ZINC CHLORIDE (EXCELA PHARMA SCIENCES)

ZINC CHLORIDE injection, USP 1 mg/mL, is indicated for use as a supplement to intravenous solutions given for total parenteral nutrition to help maintain zinc serum levels and to prevent depletion of endogenous stores and subsequent deficiency symptoms. It is supplied in an individual 10 mL vial or in cartons of 25 10 mL vials.

For more information about ZINC CHLORIDE, log in to biosupply.fffenterprises.com

POTASSIUM ACETATE (EXCELA PHARMA SCIENCES)

POTASSIUM ACETATE injection, USP 2 mEq/mL, is indicated as a source of potassium, for the addition to large volume intravenous fluids, to prevent or correct hypokalemia in patients with restricted or no oral intake; it is also useful as an additive for preparing specific intravenous fluid formulas when the needs of the patient cannot be met by standard electrolyte or nutrient solutions. It is supplied in 100 mEq/50 mL and 200 mEq/100 mL clear glass vials in cartons of one and 25.

For more information about POTASSIUM ACETATE, log in to biosupply.fffenterprises.com

POTASSIUM PHOSPHATES (AMNEAL PHARMACEUTICALS)

POTASSIUM PHOSPHATES injection is a phosphorus replacement product indicated as a source of phosphorus in intravenous fluids to correct hypophosphatemia in adults and pediatric patients when oral or enteral replacement is not possible, insufficient or contraindicated; and for parenteral nutrition in adults and pediatric patients when oral or enteral nutrition is not possible, insufficient or contraindicated. It is supplied in 15 mmol/5 mL and 22 mEq/5 mL single-dose polypropylene vials in 5 and 25 units; 45 mmol/15 mL and 66 mEq/15 mL 20 mL single-dose polypropylene vials in 10 and 25 units; and 150 mmol/50 mL and 220 mEq/50 mL bulk package polypropylene vials in 10 and 25 units.

For more information about POTASSIUM PHOSPHATES, log in to biosupply.fffenterprises.com

GAMMAGARD LIQUID (BAXALTA)

GAMMAGARD LIQUID is an immune globulin infusion (human) indicated as a replacement therapy for primary humoral immunodeficiency in adult and pediatric patients 2 years of age or older; maintenance therapy to improve muscle strength and disability in adult patients with multifocal motor neuropathy; and therapy to improve neuromuscular disability and impairment in adult patients with chronic inflammatory demyelinating polyneuropathy. It is supplied in 10 mL, 25 mL, 50 mL, 100 mL and 200 mL single-use bottles.

For more information about GAMMAGARD LIQUID, log in to biosupply.fffenterprises.com

BALFAXAR (OCTAPHARMA USA)

BALFAXAR (prothrombin complex concentrate, human-lans) is a blood coagulation factor replacement product indicated for the urgent reversal of acquired coagulation factor deficiency induced by vitamin K antagonist (VKA, e.g., warfarin) therapy in adult patients with need for an urgent surgery/invasive procedure. It is supplied in a package with either a 20 mL or a 40 mL single-dose vial of lyophilized powder and a vial of diluent (sterile water for injection), together with a transfer device.

For more information about BALFAXAR, log in to biosupply.fffenterprises.com

ZEMAIRA (CSL BEHRING)

ZEMAIRA is an alpha1-proteinase inhibitor (A1-PI; human) indicated for chronic augmentation and maintenance therapy in adults with A1-PI deficiency and clinical evidence of emphysema. It is supplied in single-dose vials containing 1,000 mg or 4,000 mg functionally active A1-PI.

For more information about ZEMAIRA, log in to biosupply.fffenterprises.com

COMIRNATY (PFIZER-BIONTECH)

COMIRNATY (mRNA) is a vaccine indicated for active immunization to prevent coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in individuals 12 years of age and older. It is supplied in cartons of 10 single-dose glass prefilled syringes, single-dose plastic prefilled syringes and single-dose vials.

For more information about COMIRNATY, log in to biosupply.fffenterprises.com

CARBOPLATIN (BPI LABS)

CARBOPLATIN injection is indicated for the initial treatment of advanced ovarian carcinoma in established combination with other approved chemotherapeutic agents, and for the palliative treatment of patients with ovarian carcinoma recurrent after prior chemotherapy, including patients who have been previously treated with cisplatin. It is supplied in 5 mL fill in 10 mL, 15 mL fill in 20 mL, 45 mL fill in 50 mL and 60 mL fill in 100 mL multiple-dose vials.

For more information about CARBOPLATIN, log in to biosupply.fffenterprises.com

CISPLATIN (ACCORD HEALTHCARE)

CISPLATIN injection is a platinum-based drug indicated for the treatment of advanced testicular cancer, advanced ovarian cancer and advanced bladder cancer. It is supplied in 50 mg/50 mL (1 mg/mL) and 100 mg/100 mL (1 mg/mL) multiple-dose amber vials.

For more information about CISPLATIN, log in to biosupply.fffenterprises.com

YCANTH™ (VERRICA PHARMACEUTICALS)

YCANTH is indicated for the topical treatment of molluscum contagiosum in adult and pediatric patients 2 years of age and older. It is supplied in a sealed glass ampule contained within a single-use applicator and enclosed in a protective paperboard sleeve. Each ampule contains 7 mg/mL of YCANTH.

For more information about YCANTH, log in to biosupply.fffenterprises.com

NOVAVAX COVID-19 VACCINE (NOVAVAX, INC)

The Novavax COVID-19 Vaccine (Adjuvanted/Protein Subunit) is a vaccine indicated for active immunization to prevent coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in individuals 12 years of age and older. It is supplied in boxes of 10 doses of two 2.5mL-5 dose multi-dose vials.

For more information about NOVAVAX COVID-19 VACCINE (ADJUVANTED/PROTEIN SUBUNIT), log in to biosupply.fffenterprises.com

MODERNA COVID-19 VACCINE (mRNA) (MODERNA U.S. INC.)

Moderna COVID-19 Vaccine (mRNA) is a vaccine indicated for active immunization to prevent coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in individuals 12 years of age and older. It is supplied in cartons of 10 5.5 mL multiple-dose vials and cartons of 10 7.5 mL multiple-dose vials.

For more information about MODERNA COVID-19 VACCINE (mRNA), log in to biosupply.fffenterprises.com

AREXVY (GLAXOSMITHKLINE)

AREXVY is a vaccine indicated for active immunization for the prevention of lower respiratory tract disease caused by respiratory syncytial virus in individuals 60 years of age and older. It is supplied as two components: a single-dose vial of lyophilized antigen component (powder) and a single-dose vial of adjuvant suspension component (liquid) (packaged without syringes or needles) in cartons of 10 vials.

For more information about AREXVY, log in to biosupply.fffenterprises.com

ABRYSVO (PFIZER INC.)

ABRYSVO is a vaccine indicated for active immunization for the prevention of lower respiration tract disease caused by respiratory syncytial virus in individuals 60 years of age and older. It is supplied in a kit that includes a vial of lyophilized antigen component, a prefilled syringe containing sterile water diluent component and a vial adapter in cartons of one, five and 10 kits.

For more information about ABRYSVO, log in to biosupply.fffenterprises.com

INDOCIN (ASSERTIO)

INDOCIN is a nonsteroidal anti-inflammatory drug indicated for moderate to severe rheumatoid arthritis, including acute flares of chronic disease; moderate to severe ankylosing spondylitis; moderate to severe osteoarthritis; acute painful shoulder (bursitis and/or tendinitis); and acute gouty arthritis. The 50 mg suppositories (indomethacin suppositories USP) are white, opaque and rectal supplied in boxes of 30.

For more information about INDOCIN, log in to biosupply.fffenterprises.com

CALCIPOTRIENE FOAM (MAYNE PHARMA)

CALCIPOTRIENE FOAM is a vitamin D analog indicated for the topical treatment of plaque psoriasis of the scalp and body in adults and pediatric patients 4 years of age and older. It is supplied in a 60 gram aluminum can.

For more information about CALCIPOTRIENE FOAM, log in to biosupply.fffenterprises.com

DORYX MPC (MAYNE PHARMA)

DORYX MPC is a tetracycline-class drug indicated for the treatment of rickettsial infections; sexually transmitted infections; respiratory tract infections; specific bacterial infections; ophthalmic infections; anthrax, including inhalational anthrax (post-exposure); alternative treatment for selected infections when penicillin is contraindicated; adjunctive therapy in acute intestinal amebiasis and severe acne; and prophylaxis of malaria. The DORYX MPC (doxycycline hyclate delayed-release) 60 mg and 120 mg tablets are white, oval tablets containing yellow pellets and debossed with "D6" on one face and plain on the other. The 60 mg tablets are supplied in bottles of 60 and 120, and the 120 mg tablet is supplied in bottles of 30.

For more information about DORYX MPC, log in to biosupply.fffenterprises.com

LIDOCAINE HYDROCHLORIDE 4% (SINTETICA US LLC)

LIDOCAINE HYDROCHLORIDE injection 4% is indicated for the production of topical anesthesia of the mucous membranes of the respiratory tract or the genito-urinary tract. It may be injected trans-tracheally to anesthetize the larynx and trachea, and it may be administered by retrobulbar injection to provide anesthesia for ophthalmic surgery. It is supplied in a pack of 10 200 mg/5 mL single-dose ampules.

For more information about LIDOCAINE HYDROCHLORIDE 4%, log in to biosupply.fffenterprises.com

LIDOCAINE HYDROCHLORIDE 1%/2% (SINTETICA US LLC)

LIDOCAINE HYDROCHLORIDE injection 1% and 2% are indicated for production of local or regional anesthesia by infiltration techniques such as percutaneous injection, by peripheral nerve block techniques such as brachial plexus and intercostal, and by central neural techniques such as lumbar and caudal epidural blocks when the accepted procedures for these techniques as described in standard textbooks are observed. The 1% injection is supplied in a pack of 10 20 mg/2mL, 50 mg/5 mL and 100 mg/10 mL single-dose ampules. The 2% injection is supplied in 40 mg/2 mL, 100 mg/5 mL and 200 mg/10 mL single-dose ampules.

For more information about LIDOCAINE HYDROCHLORIDE 1%/2%, log in to biosupply.fffenterprises.com

HEPARIN SODIUM (TECHDOW)

HEPARIN SODIUM injection is an anticoagulant indicated for prophylaxis and treatment of venous thrombosis and pulmonary embolism; prevention of postoperative deep venous thrombosis and pulmonary embolism in patients undergoing major abdominothoracic surgery or who, for other reasons, are at risk of developing thromboembolic disease; atrial fibrillation with embolization; treatment of acute and chronic consumptive coagulopathies (disseminated intravascular coagulation); prevention of clotting in arterial and cardiac surgery; prophylaxis and treatment of peripheral arterial embolism; and use as an anticoagulant in blood transfusions, extracorporeal circulation and dialysis procedures. It is supplied in a concentration of 1,000 mL in 2 mL single-dose vials and 1 mL, 10 mL and 30 mL multiple-dose vials; in a concentration of 5,000 mL in 1 mL and 10 mL multiple-dose vials; in a concentration of 10,000 mL in 1 mL and 5 mL multiple-dose vials; and in a concentration of 20,000 mL in 1 mL multiple-dose vials.

For more information about HEPARIN SODIUM, log in to biosupply.fffenterprises.com

SODIUM BICARBONATE (EXELA PHARMA SCIENCES)

SODIUM BICARBONATE injection, USP, is indicated 1) in the treatment of metabolic acidosis that may occur in severe renal disease, uncontrolled diabetes, circulatory insufficiency due to shock or severe dehydration, extracorporeal circulation of blood, cardiac arrest and severe primary lactic acidosis, 2) in the treatment of certain drug intoxications, including barbiturates (where dissociation of the barbiturate-protein complex is desired), in poisoning by salicylates or methyl alcohol and in hemolytic reactions requiring alkalinization of the urine to diminish nephrotoxicity of hemoglobin and its breakdown products and 3) in severe diarrhea that is often accompanied by a significant loss of bicarbonate. It is supplied in 50 mL vials with either 20 or 25 vials per carton, and 10 mL vials with 25 vials per carton.

For more information about SODIUM BICARBONATE, log in to biosupply.fffenterprises.com

These products can be ordered from FFF Enterprises' BioSupply Online Ordering System or by calling
Wow! Customer Care at (800) 843-7477.

Current Medicare IVIG / SCIG Rates

Rates per gram are effective January 1, 2024, through March 31, 2024.

 
Calculate Your Current Medicare IVIG/SCIG Rates
Product J Codes ASP + 6%
(before sequester)
ASP + 4.3%*
(after sequester)
IVIG
ASCENIV J1554 $982.81 $967.05
BIVIGAM J1556 $145.92 $143.58
GAMMAGARD SD J1566 $157.00 $154.48
GAMMAPLEX J1557 $110.31 $108.54
OCTAGAM J1568 $89.96 $88.51
PANZYGA J1576 $132.88 $130.75
PRIVIGEN J1459 $96.58 $95.03
SCIG
CUTAQUIG J1551 $138.88 $136.65
CUVITRU J1555 $159.22 $156.67
HIZENTRA J1559 $129.45 $127.37
HYQVIA J1575 $170.85 $168.11
XEMBIFY J1558 $141.83 $139.56
IVIG / SCIG
GAMMAGARD LIQUID J1569 $88.30 $86.89
GAMMAKED J1561 $99.57 $97.98
GAMUNEX-C J1561 $99.57 $97.98
 

Resources

FFF customers may order the following complementary resources to help you with your practice:

Seasonal Flu Poster flu myths and facts brochure
immune globulin reference charts
•  Immune Globulin (Human) Chart
•  Hyperimmune Globulin Chart
•  Coagulation Catalog
•  Seasonal Influenza Vaccine Reference Guide
   

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