Monday, July 22, 2019

Banner Image - Patient Safety, Product Integrity, Fair Pricing

HPV Vaccine Exceeds Expectations by Providing Herd Immunity

In this Issue


•	IVIG/Albumin Supply Index
•	Open Market Pricing
•	New Products from FFF
•	Current Medicare IVIG / SCIG Rates
•	Resources
•	Subscribe to IG Living and BioSupply Trends Quarterly

A new study shows the human papillomavirus (HPV) vaccine is far more effective than expected, with benefits extending beyond those who receive the vaccine. Specifically, the study showed vaccination not only reduces rates of HPV infection and the presence of precancerous cells in the cervix in people who receive the vaccine, it also reduces rates of HPV-related diseases in people who are not vaccinated. [read more]

Genetics Linked to Immunity to Childhood Vaccines

A genome-wide study, conducted by researchers at the University of Oxford in the United Kingdom, has linked a number of genetic variations with the level of protective antibodies generated following routine childhood immunizations. According to the researchers, further research may make it feasible to incorporate genetic tests into neonatal screening programs that can predict immunity to vaccines and, therefore, guide personalized vaccination regimens. [read more]

2018-19 Flu Season Separated by Two Waves Was Longest in Decade

The 2018-19 influenza (flu) season was both the longest in a decade and was marked by two separate waves of influenza A, according to the Centers for Disease Control and Prevention. During the initial surge between October and mid-February, an H1N1 strain dominated, followed by an H3N2 strain beginning in mid-February that lasted through mid-May. [read more]

Industry News

From BioLife Plasma Services

BioLife Plasma Services has opened new plasma donation centers in Mesa, Phoenix and Tempe, Ariz., advancing efforts to support patients worldwide who rely on life-changing therapies processed from donated human plasma. [read more]

From Octapharma

At the Immune Deficiency Foundation National Conference in June, Octapharma introduced its newest product, Cutaquig (immune globulin subcutaneous [human] 16.5% solution) for subcutaneous infusion indicated for treatment of primary humoral immunodeficiency (PI) in adults. The company also launched its free IgCares program, an initiative that provides a service that transforms medical waste into energy, access to educational and informational resources for PI patients and personal connections to peers, the PI community and patient advocates.
[read more]

IVIG & Albumin Supply Index

Log in to BioSupply for IVIG and Albumin Product Pricing

What's New at FFF

• FIBRYGA (OCTAPHARMA USA)

FIBRYGA is a human fibrinogen concentrate indicated for the treatment of acute bleeding episodes in adults and adolescents with congenital fibrinogen deficiency, including afibrinogenemia and hypofibrinogenemia. It is not indicated for dysfibrinogenemia. FIBRYGA packages include one single-use bottle of FIBRYGA concentrate, one transfer device (Octajet) and one particle filter.

For more information about FIBRYGA, login to biosupply.fffenterprises.com

• JIVI (BAYER HEALTHCARE)

JIVI (antihemophilic factor [recombinant], PEGylated-aucl) is a recombinant DNA-derived Factor VIII concentrate indicated for use in previously treated adults and adolescents (12 years of age and older) with hemophilia A (congenital Factor VIII deficiency) for 1) on-demand treatment and control of bleeding episodes, 2) perioperative management of bleeding and 3) routine prophylaxis to reduce the frequency of bleeding episodes. JIVI is available as a lyophilized powder in single-use glass vials, one vial per carton. It is supplied with a sterile vial adapter with a 15-micrometer filter and a prefilled diluent glass barrel syringe, that together serve as a needleless reconstitution system.

For more information about JIVI, login to biosupply.fffenterprises.com

• ANDEXXA® (PORTOLA)

ANDEXXA [coagulation factor Xa (recombinant), inactivated-zhzo] is the first and only antidote indicated for patients treated with rivaroxaban and apixaban, when reversal of anticoagulation is needed due to life-threatening or uncontrolled bleeding. It is supplied in cartons of four single-use vials containing 100 mg of ANDEXXA as a white to off-white lyophilized cake or powder.

For more information about ANDEXXA, login to biosupply.fffenterprises.com

• LidoDose® (GENSCO PHARMA)

Prepare your patients for a less painful flu season with LidoDose, the single dose™ topical anesthetic and antiseptic for preprocedural preparation of the skin prior to an injection and pain associated with any procedure requiring penetration of the skin, including vaccinations.

For more information about LidoDose, login to biosupply.fffenterprises.com

• ALBUMINEX® (BIO PRODUCTS LABORATORY)

ALBUMINEX [Human 5% and 25%], prepared from the pooled plasma of U.S. donors in FDA-licensed facilities in the U.S., comes in 5% and 25% albumin solutions indicated for adults and children for hypovolemia, ascites, hypoalbuminemia including from burns, acute nephrosis, acute respiratory distress syndrome and cardipulmonary bypass. ALBUMINEX 5% is supplied in 12.5 g and 25 g single-dose vials. ALBUMINEX 25% is supplied in 50 mL and 100 mL single-dose vials.

For more information about ALBUMINEX, login to biosupply.fffenterprises.com

These products can be ordered from FFF Enterprise's BioSupply Online Ordering System or by calling
Wow! Customer Care at (800) 843-7477.

Current Medicare IVIG / SCIG Rates

Rates per gram are effective July 1, 2019, through Sept. 30, 2019.

Product	J Codes	ASP + 6% (before sequester)	ASP + 4.3%* (after sequester)
IVIG
Flebogamma	J1572	$71.71	$70.56
Gammagard S/D	J1566	$124.44	$122.44
Gammaplex	J1557	$92.06	$90.59
Octagam	J1568	$64.94	$63.90
Privigen	J1459	$81.21	$79.90
SCIG
CUVITRU	J1555	$138.56	$136.34
Hizentra	J1559	$101.89	$100.26
HyQvia	J1575	$140.24	$137.99
IVIG / SCIG
Gammagard Liquid	J1569	$81.93	$80.62
Gammaked	J1561	$77.29	$76.05
Gamunex-C	J1561	$77.29	$76.05

*Reflects 2% sequestration reduction applied to 80% Medicare payment portion as required under Budget Control Act of 2011.

Log in to BioSupply for Immune Globulin Products

Resources

FFF customers may order the following complementary resources to help you with your practice:


•	IG Immune Globulin (Human)
•	Hyperimmune Globulins
•	Anti-Inhibitor, Factor VIIa & IX
•	Factor VIII & von Willebrand Factor
•	Seasonal Influenza Vaccine

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Trends Quarterly

BioSupply Trends Quarterly magazine is the definitive source for industry trends, news and information for the biopharmaceuticals marketplace.